Turkey Cranberry Grilled Cheese

Featured in: Thanksgiving & Christmas Ideas

Elevate your holiday leftovers with this indulgent spin on the classic grilled cheese. Buttered sourdough bread encases layers of sliced turkey breast, tangy cranberry sauce, and melting Swiss or provolone cheese. The sandwich grills to golden perfection in just 8 minutes, creating crispy exteriors with warm, gooey interiors. Perfect for a quick lunch or cozy dinner, this handheld delight captures all the flavors of the festive season in every bite.

Updated on Thu, 15 Jan 2026 16:17:00 GMT
Golden-brown sourdough grilled cheese layered with sliced turkey and cranberry sauce, melted Swiss cheese oozing from the sides on a rustic wooden board. Save
Golden-brown sourdough grilled cheese layered with sliced turkey and cranberry sauce, melted Swiss cheese oozing from the sides on a rustic wooden board. | tastyeffect.com

Last November, I stood in my kitchen staring at a mountain of Thanksgiving leftovers. The turkey containers were stacked like Jenga blocks, and that jar of cranberry sauce kept mocking me from the refrigerator door. Something about the combination clicked in my brain around midnight when hunger hit hard. I slapped everything between bread, buttered it up, and what happened next changed how I view leftovers forever.

I’ve been getting a lot of questions about the pot I use for cozy one-pot meals and small-batch recipes, so I wanted to quickly share it here.

Martha Stewart Heart Shaped Cast Iron Dutch Oven

This is the Martha Stewart heart-shaped enameled cast iron Dutch oven (2-quart). It’s one of those pieces I reach for constantly when testing soups, stews, baked casseroles, and smaller comfort-food recipes.

  • Heats evenly with no hot spots (huge for slow cooking)
  • Non-reactive enamel interior — no seasoning required
  • Perfect size for small households or side dishes
  • Sturdy handles, easy to move from oven to table

It’s also a favorite with home cooks — 4.6 out of 5 stars from over 1,900 reviews — and Amazon often has a coupon available, depending on color and size.

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My brother walked in during that first experimental batch, skeptical about cranberry sauce on a sandwich. One bite later, he was building his own with twice the cheese. Now every holiday gathering includes at least one person asking when were making these again. The way the butter soaks into sourdough while Swiss cheese bubbles over the edge creates aromas that pull everyone into the kitchen.

Ingredients

  • 4 slices sourdough or country bread: Sourdough holds up better to the weight of toppings and develops that perfect crunch
  • 2 tablespoons unsalted butter, softened: Room temperature spreads evenly without tearing the bread
  • 4 ounces cooked turkey breast, sliced: Thin slices heat through quickly and distribute throughout every bite
  • 4 tablespoons cranberry sauce: Whole berry adds texture while jellied melts into the cheese beautifully
  • 4 slices Swiss or provolone cheese: Swiss complements the tart cranberries while provolone brings creaminess

Instructions

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Prep your bread:
Spread softened butter generously on one side of each bread slice, reaching all corners to ensure even golden color
Build the layers:
Place cheese directly on unbuttered bread followed by turkey, cranberry sauce, another cheese slice, then top with remaining bread butter side out
Get the heat right:
Warm your skillet over medium heat until a drop of water sizzles gently across the surface
Careful flipping:
Cook 3 to 4 minutes per side, pressing gently with your spatula to encourage contact without crushing the sandwich
The waiting game:
Let sandwiches rest one minute after cooking so the cheese sets slightly instead of oozing out when sliced
Product image
Create smooth frozen drinks, slushies, and frappés for desserts and parties using juices, coffee, or wine.
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Savory turkey cranberry grilled cheese sandwich served warm, featuring melty provolone and tart cranberry sauce between crispy buttery bread slices. Save
Savory turkey cranberry grilled cheese sandwich served warm, featuring melty provolone and tart cranberry sauce between crispy buttery bread slices. | tastyeffect.com

These sandwiches saved our family game night last month. Everyone was too tired to cook a full meal but wanted something more substantial than cereal. The house filled with buttery, cheesy goodness and suddenly we were all sitting around the counter, trading bites and brainstorming other leftover combinations.

Perfect Pairings

A simple arugula salad with vinaigrette cuts through the richness beautifully. Sweet potato chips add crunch without competing with the main attraction. Sometimes I serve tomato soup on the side for dunking, which takes the whole experience back to childhood comfort food territory.

Cheese Swaps That Work

Sharp cheddar brings bold tanginess while brie creates an incredibly luxurious mouthfeel. Gouda adds subtle sweetness that plays nicely with cranberry. I have discovered that mixing two cheeses often yields the most interesting results.

Make It Your Own

The beauty of this sandwich lies in its adaptability based on whatever is sitting in your refrigerator. Some additions elevate it from great to unforgettable.

  • Slice some red onion thinly for sharp contrast against the sweet elements
  • Fresh arugula or spinach adds brightness and cuts through richness
  • A smear of mayonnaise inside creates an extra creamy element worth trying
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Perfect Thanksgiving leftover turkey cranberry grilled cheese, golden and toasty with melted Swiss cheese and cranberry sauce on sourdough bread. Save
Perfect Thanksgiving leftover turkey cranberry grilled cheese, golden and toasty with melted Swiss cheese and cranberry sauce on sourdough bread. | tastyeffect.com

Hope this sandwich brings as much joy to your kitchen as it has to mine. Happy cooking

Recipe FAQ

What type of bread works best?

Sourdough or country bread provides ideal structure and tangy flavor that complements the sweet cranberry sauce. The sturdy slices hold up well to grilling without becoming soggy.

Can I use different cheese?

Absolutely. Sharp cheddar adds bold flavor, brie creates creamy richness, or try gruyère for nutty notes. Choose cheeses that melt smoothly for the best results.

How do I prevent the bread from burning?

Keep the heat at medium and cook for 3–4 minutes per side. Press gently with your spatula to ensure even contact without flattening completely. Watch for deep golden brown color.

Can I make this vegetarian?

Yes, replace the turkey with sliced roasted tofu, tempeh, or additional vegetables like portobello mushrooms. The cranberry and cheese pairing remains delicious.

How should I store leftovers?

These are best enjoyed immediately while the cheese is hot and bread is crispy. If you must store, wrap in foil and reheat in a 350°F oven for 10 minutes to restore crispiness.

Turkey Cranberry Grilled Cheese

Gooey golden sandwich with leftover turkey, tart cranberry sauce, and melted cheese on buttery sourdough.

Prep duration
10 min
Cook duration
8 min
Complete duration
18 min
Created by Laura Bennett


Skill level Easy

Heritage American

Output 2 Portions

Dietary requirements None specified

Components

Bread & Spreads

01 4 slices sourdough or country bread
02 2 tablespoons unsalted butter, softened

Filling

01 4 ounces cooked turkey breast, sliced
02 4 tablespoons cranberry sauce (whole berry or jellied)
03 4 slices Swiss or provolone cheese

Optional Additions

01 2 tablespoons mayonnaise
02 1/4 red onion, thinly sliced
03 Handful of baby spinach or arugula

Directions

Phase 01

Prepare the Bread: Lay out all bread slices. Spread softened butter evenly on one side of each slice.

Phase 02

Layer the Filling: Flip two slices so the unbuttered side faces up. Layer each with 1 cheese slice, half the turkey, 2 tablespoons cranberry sauce, and any optional additions such as mayonnaise, onion, or greens. Top with another cheese slice.

Phase 03

Assemble Sandwiches: Place the remaining bread slices on top, buttered side facing outward to ensure golden grilling.

Phase 04

Heat the Cooking Surface: Preheat a nonstick skillet or griddle over medium heat until evenly warmed.

Phase 05

Grill the Sandwiches: Place sandwiches in the skillet and cook for 3–4 minutes per side, pressing gently with a spatula, until bread is golden brown and cheese is fully melted.

Phase 06

Rest and Serve: Remove from skillet, let rest for 1 minute to set, then slice diagonally in half and serve warm.

Necessary tools

  • Nonstick skillet or griddle
  • Spatula
  • Sharp knife
  • Cutting board

Allergy details

Review each component for potential allergens and seek professional healthcare advice if uncertain.
  • Contains wheat (bread), milk (butter, cheese). May contain eggs if mayonnaise is used.

Nutritional information (per portion)

These values are approximate guides only and shouldn't replace professional medical consultation.
  • Energy: 470
  • Fats: 21 g
  • Carbohydrates: 45 g
  • Proteins: 27 g